Rationale: According to the World Health Organization (2021), globally, 8% of children aged 5-9 years and 14% of adolescents aged 10-19 years live with a mental disorder. Also, half of the mental health disorders present in adulthood develop by age 14 years. (World Health Organization. World mental health report 2022). However, in Guyana, there are no statistics to depict these mental disorders in this population. Objectives: This study focused on describing characteristics of mental disorders in the pediatric population attended by the Child Psychiatry outpatient clinic of the Georgetown Public Hospital Corporation (GPHC), Guyana from 1st January 2016- 31st December 2022. Methodology: This cross-sectional study was conducted with patients aged 2 to 17 years who attended the Psychiatric clinic at GPHC from 1st Jan 2016 to 31st Dec 2022, after approval was granted from the Georgetown Public Hospital Corporation Research Committee and the Institutional Review Boards (IRB) from the Ministry of Health of Guyana. The patient records were sampled following a stratified random sampling design from a population of 1288, stratified via proportional allocation over the years 2016 to 2022. The data was collected via an Excel spreadsheet and was imported into R Core Team (2022). All statistical tests’ alpha level was set to 5% with confidence intervals and p-values were reported along with descriptive summaries highlighting trends. This research was carried out under the ethical principles that govern all research as provided for in the 2006 Helsinki Declaration. Conclusions: 1. Demographics include most frequent age between 10-17 years old (70%); female patients (51%), Afro-Guyanese (45%), 85% attended school and 48% with mothers as their legal representatives. The most common referral center was a hospital (48%), 49% referred by a doctor, 91% not in institutional care, 68% from a single parent family and majority from region 4 (76%). 2. The most common psychiatric disorders disorders were Neurodevelopmental disorders (43%), Stressor and trauma related disorders (16%), Disruptive Impulse control and conduct disorders (13%), Schizophrenia spectrum and related disorders (11%), Depressive Disorder (11%), Unspecified personality disorder (6.1%) and anxiety disorders (5.8%). 3. Associated factors of the different psychiatric disorders were family history of a mental disorder 25.4%, Previous suicide behavior 18.6%, substance use 14.8%, experience abuse 27.1%, Medical illness 12.1%, Developmental risk in 27.7%. 4. The most common diagnosis were Neurodevelopmental disorders found in 86% of patients less than age 6. Developmental risk and family history of a developmental disorder had higher incidence. Perinatal risk and medical illnesses were more prevalent in males 55.9%, seen mostly in childhood 58.4%, highest in mixed population 65.1% and 80% of the patients attended school.